PRODUCT DETAILS

About Arizex-Plus Tablet

DONEPEZIL+MEMANTINE is a combination drug containing a 'neurological medicine,' primarily used to treat Alzheimer's disease (memory loss). Alzheimer's disease is a progressive neuro disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells (neurons) to die. 

DONEPEZIL+MEMANTINE is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor that works by preventing the breakdown of the chemical acetylcholine and improving the function of nerve cells in the brain. Memantine works by lowering the level of the chemical in the brain, which is responsible to cause symptoms of Alzheimer's disease. Together, both of them balance the levels of chemical messengers in the brain and help transmit nerve signals.

Take DONEPEZIL+MEMANTINE as prescribed by your doctor. You are advised to take DONEPEZIL+MEMANTINE for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it before just bedtime. In some cases, you may experience vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhea, and headache. Most of these side effects of DONEPEZIL+MEMANTINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

DONEPEZIL+MEMANTINE may cause dizziness and sleepiness. So, do not drive a car or operate any machinery that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking DONEPEZIL+MEMANTINE as it may cause diarrhea. Before using DONEPEZIL+MEMANTINE, inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. 

Uses of Arizex-Plus Tablet

Alzheimer’s disease (memory loss)

Medicinal Benefits of Arizex-Plus Tablet

DONEPEZIL+MEMANTINE is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals. Donepezil is a cholinesterase inhibitor that works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain, which are responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.

Directions for Use

Take the tablet of DONEPEZIL+MEMANTINE with or without food or as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it. Preferably take it just before bedtime.

Side Effects of Arizex-Plus Tablet

• Vomiting
• Loss of appetite
• Dryness in the mouth
• Dizziness
• Weight loss
• Nausea
• Diarrhea
• Headache

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take DONEPEZIL+MEMANTINE if you are allergic to DONEPEZIL+MEMANTINE or any of its ingredients. DONEPEZIL+MEMANTINE may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking DONEPEZIL+MEMANTINE as it may cause diarrhea. Before using DONEPEZIL+MEMANTINE, inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. Take DONEPEZIL+MEMANTINE preferably just before bedtime.

Drug Interactions

Drug-Drug Interaction:

DONEPEZIL+MEMANTINE is known to interact with pain killers (aspirin), anticholinergics (donepezil), antiparkinson's disease (amantadine), ketamine, dextromethorphan), anti-fungal (ketoconazole),  anti-epilepsy medicines (phenytoin, carbamazepine, phenobarbital), corticosteroid (dexamethasone), anti-tuberculosis medicines (rifampin), stomach ulcer medicines (cimetidine, ranitidine), dopaminergic agonists (bromocriptine).

Drug-Disease Interaction:

 DONEPEZIL+MEMANTINE is known to interact in patients with kidney or liver disease, asthma, heart disease, history of seizures, stomach ulcers, history of intestinal bleeding, urination problems, and bladder obstruction.

Safety Advice

ALCOHOL

Taking alcohol, along with DONEPEZIL+MEMANTINE, may increase its drowsiness effect and cause excessive sleepiness.

PREGNANCY

DONEPEZIL+MEMANTINE is a pregnancy category C drug. It is not known whether it will harm the baby. So, take only if prescribed by a doctor.

BREAST FEEDING

It is not known whether DONEPEZIL+MEMANTINE passes through breast milk or not. So, caution should be exercised if you are breastfeeding.

DRIVING

DONEPEZIL+MEMANTINE is known to cause drowsiness, so please do not drive a car or operate any machinery which requires mental alertness.

LIVER

DONEPEZIL+MEMANTINE is to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

KIDNEY

DONEPEZIL+MEMANTINE is to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.